Given a structure of a transmembrane helical bundle (TMH), our server predicts its orientation of insertion into a lipid bilayer as well as the optimal hydrophobic thickness of the bilayer.

Later, by supplying the inserted protein to our recent developed coarse-grained model, Upside, we generate an ensemble of possible configurations of the protein embedded in the bilayer.

 

Dynamic orienation of 2b2h

2hb2: Ammonium Transporter Amt-1 from A. fulgidus (AS)

Dynamic orienation of 2b2h

News! We presented at BPS 2019, Baltimore (Mar. 5th, 2019).

Presentation at BPS2019

 

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